Cancer’s Vulnerability is Our Strength

Cyteir is developing the next generation of synthetic lethal therapies to treat cancer.

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Scientific Approach

At Cyteir, we employ an integrated target discovery approach that incorporates a critical evaluation of the target biology with internal and external information from a variety of genetic and chemical synthetic lethality screens to fuel our drug discovery and development pipeline. Cyteir’s wholly owned lead compound, CYT-0851, is a potent and selective, oral investigational drug currently in a Phase 1/2 clinical trial for hematologic and solid tumors.


Novel, drug candidates targeting key cancer vulnerabilities



Enrollment is open in our Phase 1/2 trial for solid tumors and hematologic malignancies



At Cyteir, patients come first, science is key and collaboration is valued. Come join us!


Cyteir’s Culture

With a pioneering spirit, putting patients first, we advance science passionately and collaboratively, in a fun learning environment. We value open, honest and transparent communication. We work diligently with respect for each other with a sense of urgency, integrity, accountability and purpose.​

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“Cyteir is a clinical stage oncology company that’s focused entirely on the discovery and development of next-generation synthetically lethal therapies for the treatment of cancer. We’re using our expertise in translating new biological discoveries to advance a pipeline of novel drugs that create synthetic lethality and target these cancer vulnerabilities.”

Markus Renschler, MD
President and Chief Executive Officer