Senior/Principal Scientist, Discovery Biology

Senior/Principal Scientist, Discovery Biology

The ideal candidate will perform high-quality, lab-based research and provide subject matter expertise in cancer cell biology to support our DDR drug discovery and development efforts. Primary responsibilities will include developing and implementing screening assays, evaluating lead compounds in secondary bioassays and mechanism of action studies, and identifying and validating new DDR targets. This individual will have a strong background in biochemistry and/or cell biology with experience in cancer drug discovery and possess a strong desire to apply their expertise to advance Cyteir’s drug discovery research in a highly interactive and collegial team environment.

Job Responsibilities:

  • Perform bench work and lead a small team of passionate scientists to discover and develop small molecule inhibitors targeting key nodes of DNA damage-response (DDR) pathways
  • Develop and implement robust and biologically relevant biochemical and cell-based assays to support compound selection and characterization
  • Deliver high-quality data to support mechanism of action studies, patient selection biomarker strategies, and combination approaches
  • Collect, analyze, and provide written and/or verbal summaries of the results of experiments to supervisor and scientific team
  • Continue to expand knowledge of cancer biology and drug discovery best practices by reading literature and attending scientific meetings
  • Act in accordance with all Cyteir Therapeutics policies and be a positive contributor to company culture

Job Qualifications:

  • Ph.D. and 4+ combined years of postdoctoral research experience and/or industry experience in small molecule cancer drug discovery
  • Deep understanding and demonstrated technical expertise in one or more of the following areas of research: cell cycle regulation, cell death mechanisms, DNA damage response and repair pathways; target ID and validation; biochemical and biophysical assay development
  • A proven track record of publishing high quality research and leading research projects
  • Hands-on laboratory experience in molecular biology, cancer cell biology, or biochemistry including extensive mammalian cell culture experience
  • Demonstrated ability to work well and contribute to a team environment
  • Proficiency in basic data analysis and visualization software
  • Positive attitude, curious, creative, and eager to learn
  • Strong analytical and problem-solving skills with the ability to multi-task
  • Well organized and able to maintain detailed records of experimental work
  • Ability to communicate clearly and decisively in an open, timely manner
  • The courage to say, “I don’t know” and to ask for help
  • A sense of adventure and excitement to help build a successful biotech company and work in a highly dynamic research environment
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Senior/Principal Scientist, Discovery Biology

APPLY NOW